1927年9月，鄂西秋收暴动的第一枪——当阳瓦仓起义打响，极大地震慑了土豪劣绅和国民党反动派。抗日战争爆发后，宜昌成为中共湖北省委、湘鄂西区党委机关所在地，领导湖北、湘鄂西地区人民顽强抗日。
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Once Koch established the methods to grow pure cultures of bacteria like tuberculosis and anthrax, he demonstrated for the first time that microbes can cause diseases, a feat that earned him the 1905 Nobel Prize in Physiology or Medicine.
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